Found 36 matching trials
Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study NA This study is looking at outcomes in people with advanced cancers who have ...
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Peter MacCallum Cancer Centre
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SAFIR-PI3K A Phase II Randomized Maintenance Trial Comparing Alpelisib and Fulvestrant Versus Chemotherapy in PIK3CA Mutated Advanced Breast Cancer PHASE2 SAFIR PI3K is an open-label multicenter phase II randomized trial, comparin...
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Institut de Cancérologie de l'Ouest/Paul Papin
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Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients PHASE2 Men and post- or induced menopausal women with ER\[+\] and/or PgR\[+\], HER...
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Hospital General Universitario de Alicante
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Pharmacokinetic Study of Alpelisib in Subjects With Hepatic Impairment. PHASE1 To characterize the pharmacokinetics and safety of alpelisib in subjects wi...
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DaVita Clinical Research-Denver
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Trial of AEB071 in Combination With BYL719 in Patients With Melanoma PHASE1 Primary objective is to define the maximum tolerated dose (MTD) for the com...
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Bascom Palmer Eye Institute of University Of Miami Medical Center
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Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-positive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aromatase Inhibitor. PHASE3 The purpose of this study is to complement Study CBYL719C2301 (SOLAR-1) and...
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Active Not Recruiting
Location
Novartis Investigative Site
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Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1) PHASE3 This is a Phase 3, open-label, randomized, clinical trial evaluating the ef...
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Active Not Recruiting
Location
University of Alabama at Birmingham
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Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women PHASE2 The purpose of the study was to determine whether treatment with a PI3K inh...
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University of Alabama at Birmingham/ Kirklin Clinic Univ AL - PI
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Alpelisib and Paclitaxel in PIK3CA-altered Gastric Cancer PHASE1 Alpelisib (BYL719) is a PIK3CA-specific inhibitor, which was developed by N...
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Seoul National University Bundang Hospital
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Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer PHASE1 This is a multicenter, Phase 1b/2 trial in participants with estrogen recep...
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Active Not Recruiting
Location
Dothan Hematology and Oncology
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